Cardiac magnetic resonance imaging in differential diagnosis of cardiac masses

Abstract Funding Acknowledgements Type of funding sources: Public hospital(s). Main source(s): S. Orsola Hospital Background Differential diagnosis cardiac masses represents a challenging issue with important implications for therapeutic management and patient’s prognosis. Cardiac Magnetic Resonance (CMR) is non-invasive imaging technique used to characterize morphologic functional features masses. Integration these information can lead an accurate diagnosis. Purpose To evaluate the diagnostic role CMR in defining nature Methods : Ninety-three patients evaluated were enrolled. All had histological certainty. sequences allowed qualitative description as well tissue characterization. Evaluation morphology included localization, size borders assessment, detection potential multiple lesions pericardial effusion. Tissue characterization resulted from estimation contrast enhancement - early gadolinium (EGE) late (LGE) homogeneity T1 T2 weighted acquisitions. The descriptive analysis was carried out by comparing benign vs malignant dividing into 4 subgroups: primitive tumours, metastatic tumours pseudotumours. Results showed that diameter > 50mm, invasion surrounding planes, irregular margins presence effusion able predict malignancy (p < 0.001). As characteristics, heterogeneous signal intensity independently acquisitions EGE more common <0.001). When analysing four subgroups, did not discriminate between metastasis. Conversely, hyperintensity distinguish pseudotumors = 0.002). Furthermore, using classification regression tree (CART) analysis, we developed algorithm differentiate masses: planes characteristic identifies itself tumors. In absence invasive features, evaluated: lack uptake exclude pseudotumor reduced probability primary tumor. Conclusions magnetic resonance very powerful tool differential it correctly addresses malignancy. evaluation several may Figure. Benign